✦ WOMO Approved Picks ✦
Fourteen ailment categories. Every supplement is something Mae would recommend in the app — chosen because the research supports it and women have actually felt the difference.
WOMO Health is bio-intelligence — not medical advice. The supplements below support specific symptoms but are NOT a replacement for medical care. Always talk to a women's-health-literate doctor before starting anything new — especially if you're pregnant, nursing, on prescription medications, managing a chronic condition, or scheduled for surgery within 2 weeks.
Some herbs and supplements interact with prescription drugs in ways that can be serious. We've marked the high-risk products with specific warnings. Read them. If you have any doubt, ask a pharmacist or doctor first.
26 million American women live with undiagnosed fibroids. By age 50, 80% of Black women will develop them. Fibroids feed on estrogen dominance and chronic inflammation. The supplements below support estrogen metabolism, iron levels lost to heavy bleeding, and the uterine muscle itself.
Research: NIH, American Journal of Obstetrics & Gynecology, Endometriosis Foundation
Diindolylmethane helps the liver metabolize excess estrogen — the hormone fibroids feed on. The single most-recommended supplement for estrogen dominance.
Heavy periods drain iron — bisglycinate is the gentle, well-absorbed form that doesn't constipate. Ask your doctor about ferritin (not just hemoglobin) under 50.
Regulates progesterone and LH naturally. Supports cycle regularity, eases PMS, helps offset estrogen dominance. Best results after 2–3 months.
PCOS affects 1 in 10 women and is at its core a metabolic and hormonal condition — not just irregular cycles. Insulin resistance drives most of the chaos: weight gain, acne, hair growth, missed ovulation. The 40:1 inositol ratio is the standard backed by clinical research.
Research: PCOS Awareness Association, European Review for Medical and Pharmacological Sciences, NIH
The most researched PCOS supplement. Supports insulin sensitivity, ovulation, and androgen balance. The 40:1 ratio is what the clinical studies used.
Shop on Amazon →Two cups a day shown in studies to lower free testosterone in women with PCOS — supporting clearer skin and slower facial hair growth.
Shop on Amazon →Often called "nature's metformin." Multiple studies show it improves insulin sensitivity and blood sugar in PCOS.
Boosts glutathione, supports ovulation, improves insulin response. Often paired with inositol for PCOS protocols.
An Andean root that supports energy, libido, and overall hormone balance — without containing hormones itself.
Shop on Amazon →Perimenopause starts in the late 30s for many women and lasts up to 10 years. Hormones swing wildly. Sleep breaks. Mood shifts. Cortisol creeps up. The supplements below address the actual mechanisms — cortisol regulation, breast tenderness, sleep, night sweats.
Research: Menopause Society, Journal of Mid-Life Health, Cleveland Clinic
The most-researched adaptogen for cortisol. Lowers stress hormones, supports thyroid, helps sleep. KSM-66 is the clinical-grade extract used in studies.
Rich in GLA, an omega-6 fatty acid that supports hormone signaling and reduces cyclical breast tenderness.
80% of women are magnesium deficient. The glycinate form is best absorbed and gentle on the gut — supports sleep, anxiety, period cramps.
Shop on Amazon →Endometriosis affects 1 in 10 women — same prevalence as diabetes — yet the average time to diagnosis is 7 to 10 years. While you wait, the inflammation does damage. These tools target prostaglandin-driven uterine spasm and inflammation itself.
Research: Endometriosis Foundation of America, WHO, Cochrane Reviews
A traditional women's herb that relaxes uterine muscle spasm. Take at the first twinge. Works faster than waiting for ibuprofen.
Shop on Amazon →EPA and DHA reduce the prostaglandins that drive period pain. Multiple studies show measurable reduction in pain scores with daily use.
Magnesium is a smooth-muscle relaxant — including the uterine muscle. Daily use (not just during your period) is the protocol that works.
Shop on Amazon →299,000 women die from heart disease every year — yet 70% of clinical trial participants are men. Women's symptoms are different, dismissed more often, undertreated. The foundational supplements below address the basics: vitamin D, omega-3, magnesium.
Research: American Heart Association, CDC, JAMA Cardiology
Most women are deficient in vitamin D. The D3+K2 combo ensures calcium goes to your bones — not your arteries.
Lowers triglycerides, supports brain health, reduces inflammation in blood vessels. EPA and DHA linked to lower cardiovascular risk in women.
Shop on Amazon →Supports healthy blood pressure, heart rhythm, and sleep — three things tightly linked.
Shop on Amazon →A specific bacterial population in the gut — the estrobolome — controls how your body metabolizes estrogen. When that population is off, estrogen recirculates instead of being cleared. The result: cycle issues, mood shifts, and weight that won't move.
Research: Microbiome Journal, American Society for Microbiology, NIH Estrobolome Studies
Contains the specific Lactobacillus strains the female microbiome needs. Supports both gut and intimate health.
Works with your gut microbiome to help the liver metabolize estrogen properly. Helpful for estrogen-dominant symptoms.
Reduces gut inflammation and supports the integrity of the intestinal lining. Foundational for the gut-hormone-mood axis.
Shop on Amazon →If you're waking at 3 a.m. with a racing heart, it isn't anxiety — it's cortisol. Women's cortisol curves change with cycle and age, and chronic stress flattens them. The supplements below address cortisol regulation and nervous-system calming — not just sedation.
Research: Journal of Clinical Endocrinology & Metabolism, Sleep Foundation, NAMS
The most-deficient mineral in women. Calms the nervous system, supports deep sleep, eases muscle tension. Start with 300mg before bed.
Shop on Amazon →Lowers cortisol over 8 weeks of consistent use. The clinical extract used in most studies. Take morning or early evening — not right before bed.
An amino acid from green tea that promotes alpha-brain-wave activity — calm focus without sedation. Great for the racing 3am brain.
Shop on Amazon →Women are twice as likely to be diagnosed with anxiety and depression — and twice as likely to be told it's "all in their head." Mood is deeply tied to hormones, gut health, blood sugar, and nutrient status.
Research: American Journal of Psychiatry, Journal of Affective Disorders, NIH Women's Health Initiative
The active form of B6, essential for making serotonin and GABA. Helpful for PMS-related mood swings and water retention.
Shop on Amazon →Multiple meta-analyses show EPA-heavy omega-3s reduce depression symptoms. The brain is 60% fat — feed it the right kind.
Shop on Amazon →Vitamin D deficiency is linked to depression in multiple studies. Most U.S. women are deficient — especially in winter.
Iron deficiency is the most common nutrient deficiency in menstruating women — and most doctors only test hemoglobin, missing the warning sign: low ferritin. Ferritin under 50 ng/mL means depleted iron stores even if hemoglobin looks normal.
Research: American Society of Hematology, Journal of Women's Health, WHO
The most absorbable iron form that doesn't cause constipation. Take with vitamin C to boost absorption. Best on empty stomach.
Take with iron to dramatically boost absorption. Also supports immune function and collagen production. Look for buffered forms if you have a sensitive stomach.
Shop on Amazon →A traditional women's herb naturally rich in iron, calcium, and minerals. Drink during your period to replenish what's lost.
Shop on Amazon →1 in 8 women will develop a thyroid disorder in her lifetime — and most are misdiagnosed as depression or "just tired." Standard TSH tests miss it. You need a full panel: TSH, Free T3, Free T4, and antibodies (TPO, TG). With thyroid, testing comes first.
Research: American Thyroid Association, Journal of Clinical Endocrinology & Metabolism
The thyroid uses more selenium than any other tissue. Helpful for women with Hashimoto's antibodies. Don't exceed 400mcg/day.
Essential for converting T4 (inactive) to T3 (active). Most women are mildly deficient. Take with food.
Shop on Amazon →Vitamin D deficiency is linked to higher TPO antibodies in Hashimoto's. Optimizing D levels is one of the cheapest interventions.
Women lose bone density rapidly around menopause as estrogen drops. By the time you're told you have osteoporosis, you've already lost 25-30% of bone mass. Bone is living tissue. With the right nutrients and weight-bearing movement, it rebuilds. Start before you need to.
Research: International Osteoporosis Foundation, Journal of Bone and Mineral Research
D3 helps you absorb calcium. K2 directs that calcium INTO your bones — not into your arteries. The combination matters more than either alone.
Bones are 60% magnesium. Most women are deficient, which means even with enough calcium, bones aren't rebuilding. Take 300-400mg daily.
Shop on Amazon →The bone-derived form of calcium — better absorbed than carbonate. Look for one paired with magnesium and K2 for full skeletal support.
Pregnancy depletes a woman of iron, folate, omega-3s, magnesium, and B vitamins. Postpartum, those depletions persist for years if untreated — and contribute to "mom brain," fatigue, mood changes, slow recovery. Always confirm with your OB or midwife.
Research: American College of Obstetricians and Gynecologists (ACOG), WHO Maternal Nutrition
Methylfolate is the active form of folate — better absorbed than synthetic folic acid. Critical in first trimester for neural tube development.
Baby's brain is 60% fat. DHA is the building block. Studies show prenatal DHA reduces postpartum depression risk for mom too.
Pregnancy and birth often leave women anemic for months. Bisglycinate is gentle, doesn't constipate, and is safe while breastfeeding (confirm with provider).
Cyclical breast tenderness, fibrocystic changes, and dense breast tissue are common — and mostly tied to estrogen dominance, low iodine, and inflammation. Supporting estrogen metabolism, iodine status, and inflammation can ease the cyclical pain nobody talks about.
Research: National Breast Cancer Foundation, American Journal of Clinical Nutrition, Journal of Reproductive Medicine
Rich in GLA, which supports hormone balance and reduces cyclical breast tenderness. A classic women's-health staple.
Helps the liver metabolize estrogen properly — important for fibrocystic breast changes and dense breast tissue. Give it 3 months.
Breast tissue concentrates iodine. Low iodine is linked to fibrocystic changes. Pair with selenium for safer dosing.
Cystic acne on your chin? Hair thinning at the temples? Stubborn melasma? These aren't cosmetic problems — they're hormonal signals. Most "beauty supplements" miss the root cause. The supplements below address the hormonal drivers: androgens, estrogen detox, gut microbiome, and collagen building blocks.
Research: Journal of Clinical and Aesthetic Dermatology, American Academy of Dermatology
Two cups a day clinically shown to lower free testosterone — the driver of hormonal acne and unwanted facial hair. Give it 3 months.
Shop on Amazon →Critical for skin healing, hormone balance, and hair follicle health. Most women with cystic acne and hair shedding are deficient.
Shop on Amazon →Supports skin elasticity, hair strength, and joint health. Especially important in perimenopause when collagen production drops with estrogen.
Shop on Amazon →✦ The Real Tool ✦
The supplements above support specific symptoms. But the real shift happens when something is actually tracking your body day by day — noticing patterns, catching changes, and answering you when you ask. That's what WOMO is for.
Join WOMO Health →Affiliate disclosure: WOMO Health earns a small commission on Amazon purchases made through links on this page. This funds the platform and never affects your price. We only recommend products we believe in. As an Amazon Associate, WOMO Health earns from qualifying purchases.
Medical disclaimer: The information on this page is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Statements regarding dietary supplements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.